Yes, the classic Quake game has been ported to "the iPhone with native OpenGL graphics and multiplayer support -- includes unique controls and menu overlays that make it easy to play." Video after the break.
The graphics were rotated to landscape mode using the full screen resolution of 480 x 320 and native Open GL ES. Numerous optimizations were added to make full use of the iPhone?s PowerVR MBX GPU.[via Toucharcade]
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[Source: Tech Blog]