That's right, a modder created a "PSX64 interface for plugging his PS2 Guitar Hero guitar into the C64, which he's having produced for sale alongside a 5 1/4-inch floppy disk of Shredz64." Video after the break.
In case you need a refresher, Shredz64 is all about bringing a Guitar Hero-style experience to the Commodore 64 -- which, in addition to holding much sentimental value, is quite the musical device in its own right[via Engadget]
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[Source: Tech Blog]